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| Molecular Profile | APC wild-type |
| Therapy | TASIN-1 |
| Indication/Tumor Type | colorectal cancer |
| Response Type | resistant |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| APC wild-type | colorectal cancer | resistant | TASIN-1 | Preclinical - Cell line xenograft | Actionable | In a preclinical study, TASIN-1 did not inhibit survival of APC wild-type colorectal cancer cells in culture or in cell line xenograft models (PMID: 27798265). | 27798265 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (27798265) | Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer. | Full reference... |