Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Molecular Profile | APC G1416* |
| Therapy | TASIN-1 |
| Indication/Tumor Type | colorectal cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| APC G1416* | colorectal cancer | sensitive | TASIN-1 | Preclinical - Cell culture | Actionable | In a preclinical study, TASIN-1 inhibited survival of colorectal cancer cell lines harboring APC G1416* in culture (PMID: 27798265). | 27798265 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (27798265) | Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer. | Full reference... |