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Molecular Profile | APC G1416* |
Therapy | TASIN-1 |
Indication/Tumor Type | colorectal cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
APC G1416* | colorectal cancer | sensitive | TASIN-1 | Preclinical - Cell culture | Actionable | In a preclinical study, TASIN-1 inhibited survival of colorectal cancer cell lines harboring APC G1416* in culture (PMID: 27798265). | 27798265 |
PubMed Id | Reference Title | Details |
---|---|---|
(27798265) | Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer. | Full reference... |