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Profile Treatment Approach Name | PIK3CB inhibitor |
Profile Name | PTEN loss |
Drug Class | PIK3CB inhibitor 8 |
Therapy |
PubMed Id | Reference Title | Details |
---|---|---|
(23674493) | PI3K pathway dependencies in endometrioid endometrial cancer cell lines. | Full reference... |
(25514658) | Discovery of (R)-8-(1-(3,5-difluorophenylamino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide (AZD8186): a potent and selective inhibitor of PI3Kβ and PI3Kδ for the treatment of PTEN-deficient cancers. | Full reference... |
(26645196) | Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy. | Full reference... |