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Profile Treatment Approach Name | FLT3 Inhibitor |
Profile Name | CBL L399V |
Drug Class | FLT3 Inhibitor 69 |
Therapy |
PubMed Id | Reference Title | Details |
---|---|---|
(25477533) | Molecular pathways: cbl proteins in tumorigenesis and antitumor immunity-opportunities for cancer treatment. | Full reference... |
(22990016) | Flt3 inhibitor AC220 is a potent therapy in a mouse model of myeloproliferative disease driven by enhanced wild-type Flt3 signaling. | Full reference... |
(19276253) | CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes. | Full reference... |