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Profile Treatment Approach Name | MEK inhibitor (Pan) |
Profile Name | MAP2K1 I111_I112del |
Drug Class | MEK inhibitor (Pan) 26 |
Therapy |
PubMed Id | Reference Title | Details |
---|---|---|
(18632602) | Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma. | Full reference... |
(18223206) | Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy. | Full reference... |