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Ref Type
PMID
Authors Shugaku Takeda, Celia Andreu-Agullo, Subhasree Sridhar, Nils Halberg, Ivo C. Lorenz, Sohail Tavazoie, Isabel Kurth, Masoud Tavazoie
Title Characterization of the anti-cancer and immunologic activity of RGX-019, a novel pre-clinical stage humanized monoclonal antibody targeting the MERTK receptor
Journal Vol Issue Date Pages Journal Short Title
AACR Annual Meeting 2019 Online Proceedings
URL https://www.abstractsonline.com/pp8/#!/6812/presentation/9185
Abstract Text AACR Annual Meeting 2019, Abstract LB-277

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
RGX-019 RGX-019 0 0
Drug Name Trade Name Synonyms Drug Classes Drug Description
RGX-019 RGX019|RGX 019 MERTK Antibody 1 RGX-019 is a monoclonal antibody that selectively targets Mertk for internalization and degradation, leading to inhibition of cancer cell growth (AACR Annual Meeting 2019, Abstract LB-277).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References