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Ref Type | Journal Article | ||||||||||||
PMID | (16774045) | ||||||||||||
Authors | Stoeckel J, Hay JG | ||||||||||||
Title | Drug evaluation: Reolysin--wild-type reovirus as a cancer therapeutic. | ||||||||||||
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Abstract Text | Oncolytics Biotech is developing an oncolytic reovirus therapy (Reolysin, Reosyn) for the potential treatment of a variety of Ras-mediated cancers, including glioma and medulloblastoma, pancreatic, prostate, breast, lung, colon, bladder, ovarian and hematological cancers, and melanoma and childhood sarcoma. Phase I/II clinical trials in recurrent malignant glioma began in 2002. |