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PMID (34378333)
Authors Mitsumura T, Kumaki Y, Takahashi K, Matsudera S, Sakakibara R, Honda T, Ishizuka M, Iijima Y, Shirai T, Okamoto T, Tateishi T, Sakashita H, Miyake S, Ikeda S, Miyazaki Y
Title Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases.
Journal Vol Issue Date Pages Journal Short Title
Thoracic cancer 12 18 2021 09 2508-2512 Thorac Cancer
URL
Abstract Text Of the 80 solid tumor cases in which liquid biopsy (LB) was performed using Guardant360 in the PROFILE study, nine were lung cancer cases. Here, we review three cases in which LB was useful in diagnosing ALK fusion-positive lung cancer, selecting sequential ALK-tyrosine kinase inhibitors, confirming uncommon EGFR mutations, and receiving biomarker-compatible therapy.

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