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PMID (34590045)
Authors Su PL, Lin CY, Chen YL, Chen WL, Lin CC, Su WC
Title Durable Response to Combined Dabrafenib and Trametinib in a Patient With BRAF K601E Mutation-Positive Lung Adenocarcinoma: A Case Report.
Journal Vol Issue Date Pages Journal Short Title
JTO clinical and research reports 2 8 2021 Aug 100202 JTO Clin Res Rep
URL
Abstract Text Targeted therapy with combined dabrafenib and trametinib has been proven to provide clinical benefits in patients with NSCLC with a BRAF V600E mutation. Nevertheless, the treatment strategy for patients with NSCLC with BRAF non-V600E mutations remains limited. Here, we present a patient with NSCLC with a BRAF K601E mutation, a class II BRAF mutation, who had a durable response to targeted therapy with combined dabrafenib and trametinib.

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