Therapy Detail
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| Therapy Name | RTX-240 |
| Synonyms | |
| Therapy Description |
RTX-240 is a therapy comprised of allogeneic red blood cells (RBCs) engineered to express a fusion protein consisting of the cytokine IL-15 and the IL-15 receptor alpha and TNFSF9 (4-1BBL), which may lead to activation of immune cells and antibody-dependent cell mediated cytotoxicity (ADCC) induced tumor cell killing (NCI Drug Dictionary; Journal for ImmunoTherapy of Cancer 2020;8). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| RTX-240 | RTX 240|RTX240 | RTX-240 is a therapy comprised of allogeneic red blood cells (RBCs) engineered to express a fusion protein consisting of the cytokine IL-15 and the IL-15 receptor alpha and TNFSF9 (4-1BBL), which may lead to activation of immune cells and antibody-dependent cell mediated cytotoxicity (ADCC) induced tumor cell killing (NCI Drug Dictionary; Journal for ImmunoTherapy of Cancer 2020;8). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04372706 | Phase Ib/II | RTX-240 | RTX-240 Monotherapy | Terminated | USA | 0 |
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