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Therapy Name	Gemcitabine + GP-2250
Synonyms
Therapy Description

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Drug Name	Trade Name	Synonyms	Drug Classes	Drug Description
Gemcitabine	Gemzar	Difluorodeoxycytidine Hydrochlorothiazide\|LY-188011	Chemotherapy - Antimetabolite 14	Gemzar (gemcitabine) is converted in cells to difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP), which act to inhibit ribonucleoside reductase and as a deoxynucleotide analog respectively, resulting in DNA strand termination and apoptosis (NCI Drug Dictionary).
GP-2250		GP 2250\|GP2250\|substance 2250		GP-2250 is an analog of Taurultam that induces reactive oxygen species (ROS) production, potentially resulting in reduced cell viability and proliferation, increased apoptosis, and inhibition of tumor growth (PMID: 28340556).

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Filtering

Case insensitive filtering will display rows if any text in any cell matches the filter term
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Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile	Indication/Tumor Type	Response Type	Therapy Name	Approval Status	Evidence Type	Efficacy Evidence	References
No data available in table

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Filtering

Case insensitive filtering will display rows if any text in any cell matches the filter term
Use simple literal full or partial string matches
Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Clinical Trial	Phase	Therapies	Title	Recruitment Status	Covered Countries	Other Countries
NCT03854110	Phase Ib/II	Gemcitabine + GP-2250 GP-2250	Trial to Evaluate Safety and Tolerability of GP-2250 in Combination With Gemcitabine	Active, not recruiting	USA	0

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