Therapy Detail
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| Therapy Name | Calcipotriene + Fluorouracil |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Calcipotriene | Dovonex | Calcipotriol | Dovonex (calcipotriene) is a synthetic vitamin D derivative that inhibits proliferation in normal and cancer cells (PMID: 26224368). | |
| Fluorouracil | Adrucil | 5-FU|5-Fluorouracil | Chemotherapy - Antimetabolite 14 | Adrucil (fluorouracil) is an antimetabolite chemotherapeutic agent that interferes with DNA and RNA synthesis, thereby preventing cancer cell growth (PMID: 28520376). Adrucil (fluorouracil) is FDA-approved for use in patients with adenocarcinoma of the colon, rectum, breast, stomach, and pancreas (FDA.gov). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03370406 | Phase I | Calcipotriene + Fluorouracil Fluorouracil | Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC | Recruiting | USA | 0 |
| NCT04329221 | Phase II | Fluorouracil Calcipotriene + Fluorouracil | Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients | Withdrawn | USA | 0 |
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