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| Therapy Name | Calcipotriene + Fluorouracil |
| Synonyms | |
| Therapy Description | |
| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Calcipotriene | Dovonex | Calcipotriol | Dovonex (calcipotriene) is a synthetic vitamin D derivative that inhibits proliferation in normal and cancer cells (PMID: 26224368). | |
| Fluorouracil | Adrucil | 5-FU|5-Fluorouracil | Chemotherapy - Antimetabolite 14 | Adrucil (fluorouracil) is an antimetabolite chemotherapeutic agent, which interferes with DNA and RNA synthesis thereby preventing cancer cell growth and is FDA approved for colorectal, breast, stomach, and pancreatic cancer (FDA.gov). |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03370406 | Phase I | Calcipotriene + Fluorouracil Fluorouracil | Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC | Recruiting | USA | 0 |
| NCT04329221 | Phase II | Fluorouracil Calcipotriene + Fluorouracil | Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients | Withdrawn | USA | 0 |