Therapy Detail
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| Therapy Name | DPV-001 |
| Synonyms | |
| Therapy Description |
DPV-001 is a cancer vaccine consisting of dendritic cell targeting microvesicles (DRibbles), which are autophagosomes derived from two non-small cell lung carcinoma cell lines (UbiLT3 and UbiLT6) that contain numerous tumor-associated antigens, including DAMPs, and delivers stable short-lived proteins (SLiPs) and defective ribosomal products (DRiPs), potential resulting in the induction of antitumor immune response (JITC 2015; 3(Suppl 2): P435; JITC 2013; 1(Suppl 1): P260). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| DPV-001 | DPV 001|DPV001 | DPV-001 is a cancer vaccine consisting of dendritic cell targeting microvesicles (DRibbles), which are autophagosomes derived from two non-small cell lung carcinoma cell lines (UbiLT3 and UbiLT6) that contain numerous tumor-associated antigens, including DAMPs, and delivers stable short-lived proteins (SLiPs) and defective ribosomal products (DRiPs), potential resulting in the induction of antitumor immune response (JITC 2015; 3(Suppl 2): P435; JITC 2013; 1(Suppl 1): P260). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|
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