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Therapy Name SGN-B6A
Synonyms
Therapy Description

SGN-B6A is an antibody-drug conjugate (ADC) comprising a monoclonal antibody targeting integrin beta-6 linked to monomethyl auristatin E, which delivers the anti-microtubule agent to integrin beta-6-expressing tumor cells, potentially resulting in inhibition of tumor growth (PMID: 37619980).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
SGN-B6A SGN B6A|SGNB6A|anti-integrin beta-6/MMAE ADC SGN-B6A SGN-B6A is an antibody-drug conjugate (ADC) comprising a monoclonal antibody targeting integrin beta-6 linked to monomethyl auristatin E, which delivers the anti-microtubule agent to integrin beta-6-expressing tumor cells, potentially resulting in inhibition of tumor growth (PMID: 37619980).

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04389632 Phase I SGN-B6A A Study of SGN-B6A in Advanced Solid Tumors Recruiting USA | GBR | FRA | ESP | CHE 1


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