Therapy Detail
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| Therapy Name | Safingol |
| Synonyms | |
| Therapy Description |
Kynacyte (safingol) inhibits protein kinase C (PKC), potentially resulting in increased tumor cell death and increased sensitivity to other anti-cancer agents (PMID: 15929099, PMID: 9815717). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Safingol | Kynacyte|Sphinganine | PKC Inhibitor (Pan) 11 | Kynacyte (safingol) inhibits protein kinase C (PKC), potentially resulting in increased tumor cell death and increased sensitivity to other anti-cancer agents (PMID: 15929099, PMID: 9815717). |
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- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT01553071 | Phase I | Safingol Fenretinide | Phase I Trial of IV Fenretinide (4-HPR) Plus IV Safingol for Patients With Relapsed Malignancies | Terminated | USA | 0 |
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