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Therapy Name IO-202
Synonyms
Therapy Description

IO-202 is a monoclonal antibody against LILRB4, which blocks downstream signaling, potentially resulting in activation of innate immune responses and inhibition of tumor growth (Blood 2020 Nov 5, 136 (Supplement 1):19-20).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
IO-202 IO202|IO 202 IO-202 is a monoclonal antibody against LILRB4, which blocks downstream signaling, potentially resulting in activation of innate immune responses and inhibition of tumor growth (Blood 2020 Nov 5, 136 (Supplement 1):19-20).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04372433 Phase I Azacitidine + IO-202 IO-202 Azacitidine + IO-202 + Venetoclax IO-202 as Monotherapy and IO-202 Plus Azacitidine +/- Venetoclax in Patients in AML and CMML Active, not recruiting USA 0
NCT05309187 Phase I IO-202 + Pembrolizumab IO-202 Dose-Escalation and Dose-Expansion Study of IO-202 and IO-202+Pembrolizumab in Solid Tumors Completed USA 0


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