Therapy Detail
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| Therapy Name | 6MHP vaccine + NeoAg-mBRAF + Poly ICLC |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| 6MHP vaccine | 6MHP vaccine is a peptide vaccine containing 6 melanoma helper peptides as epitopes, which may stimulate TH1-biased immune response against tumor cells expressing these antigens (PMID: 25126421, PMID: 26258314). | |||
| NeoAg-mBRAF | NeoAg mBRAF|BRAF 585-614 (V600E)|BRAF585-614-V600E|BRAF 585-614 V600E | NeoAg-mBRAF is a peptide consisting of aa 585-614 of the Braf protein with the BRAF V600E mutation, which may lead to cytotoxic T-lymphocyte mediated immune response against BRAF V600E-expressing tumor cells (NCI Drug Dictionary). | ||
| Poly ICLC | Hiltonol | Hiltonol (poly ICLC) is a synthetic double stranded RNA complex, which induces interferon production and stimulates anti-tumor immune response (PMID: 22126373). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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