Therapy Detail
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| Therapy Name | CAM-H2 |
| Synonyms | |
| Therapy Description |
CAM-H2 is a targeted radionuclide therapy consisting of a single domain antibody targeting Erbb2 conjugated to radioactive iodine I-131, which may inhibit tumor growth (Annals of Oncology (2019) 30 (suppl_3): iii47-iii64. 10.1093/annonc/mdz100, J. Clin. Oncol. 2018;36:e13017. doi: 10.1200/JCO.2018.36.15_suppl.e13017). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| CAM-H2 | CAMH2|CAM H2 | HER2 (ERBB2) Antibody 76 | CAM-H2 is a targeted radionuclide therapy consisting of a single domain antibody targeting Erbb2 conjugated to radioactive iodine I-131, which may inhibit tumor growth (Annals of Oncology (2019) 30 (suppl_3): iii47-iii64. 10.1093/annonc/mdz100, J. Clin. Oncol. 2018;36:e13017. doi: 10.1200/JCO.2018.36.15_suppl.e13017). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04467515 | Phase Ib/II | CAM-H2 | A Study to Evaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) Cancer | Terminated | USA | CAN | 0 |
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