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Therapy Name	AIC100
Synonyms
Therapy Description	AIC100 is a cell therapy consisting of T lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting the intercellular adhesion molecule-1 (ICAM-1), and CD28, potentially leading to activation of inhibitory T cells, inhibition of cell proliferation and inhibition of tumor growth (PMID: 31337787, NCI Drug Dictionary).

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Drug Name	Trade Name	Synonyms	Drug Classes	Drug Description
AIC100		AIC-100\|AIC 100		AIC100 is a cell therapy consisting of T lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting the intercellular adhesion molecule-1 (ICAM-1), and CD28, potentially leading to activation of inhibitory T cells, inhibition of cell proliferation and inhibition of tumor growth (PMID: 31337787, NCI Drug Dictionary).

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Case insensitive filtering will display rows if any text in any cell matches the filter term
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Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile	Indication/Tumor Type	Response Type	Therapy Name	Approval Status	Evidence Type	Efficacy Evidence	References

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Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial	Phase	Therapies	Title	Recruitment Status	Covered Countries	Other Countries
NCT04420754	Phase I	AIC100	Study of AIC100 CAR T Cells in Relapsed/Refractory Thyroid Cancer	Active, not recruiting	USA	0

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