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Therapy Name NM21-1480
Synonyms
Therapy Description

NM21-1480 is a recombinant, trispecific monovalent antibody-based molecule that targets PD-L1, 4-1BB, and human serum albumin, potentially resulting in activation of T cell immune responses and enhanced T cell-mediated cytotoxicity, leading to inhibition of tumor cell proliferation (NCI Drug Dictionary, Cancer Research 80(16), Abstr 2276).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
NM21-1480 NM21 1480|NM211480|ND 021|ND-021|ND021 NM21-1480 is a recombinant, trispecific monovalent antibody-based molecule that targets PD-L1, 4-1BB, and human serum albumin, potentially resulting in activation of T cell immune responses and enhanced T cell-mediated cytotoxicity, leading to inhibition of tumor cell proliferation (NCI Drug Dictionary, Cancer Research 80(16), Abstr 2276).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04442126 Phase Ib/II NM21-1480 A Study of NM21-1480 in Adult Patients With Advanced Solid Tumors Terminated USA | ESP 1


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