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Therapy Detail
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| Therapy Name | NM21-1480 |
| Synonyms | |
| Therapy Description |
NM21-1480 is a recombinant, trispecific monovalent antibody-based molecule that targets PD-L1, 4-1BB, and human serum albumin, potentially resulting in activation of T cell immune responses and enhanced T cell-mediated cytotoxicity, leading to inhibition of tumor cell proliferation (NCI Drug Dictionary, Cancer Research 80(16), Abstr 2276). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| NM21-1480 | NM21 1480|NM211480|ND 021|ND-021|ND021 | NM21-1480 is a recombinant, trispecific monovalent antibody-based molecule that targets PD-L1, 4-1BB, and human serum albumin, potentially resulting in activation of T cell immune responses and enhanced T cell-mediated cytotoxicity, leading to inhibition of tumor cell proliferation (NCI Drug Dictionary, Cancer Research 80(16), Abstr 2276). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04442126 | Phase Ib/II | NM21-1480 | A Study of NM21-1480 in Adult Patients With Advanced Solid Tumors | Terminated | USA | ESP | 1 |
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