Therapy Detail
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| Therapy Name | SEA-CD70 |
| Synonyms | |
| Therapy Description |
SEA-CD70 is a non-fucosylated monoclonal anti-CD70 antibody that inhibits signaling via CD27, which may lead to enhanced tumor cell killing via antibody-dependent mechanisms and inhibit tumor growth (Blood (2020) 136 (Supplement 1): 23; Blood (2020) 136 (Supplement 1): 23-24). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| SEA-CD70 | SEACD70|SEA CD70 | SEA-CD70 is a non-fucosylated monoclonal anti-CD70 antibody that inhibits signaling via CD27, which may lead to enhanced tumor cell killing via antibody-dependent mechanisms and inhibit tumor growth (Blood (2020) 136 (Supplement 1): 23; Blood (2020) 136 (Supplement 1): 23-24). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04227847 | Phase I | SEA-CD70 | A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies | Recruiting | USA | NLD | 0 |
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