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Therapy Name T3011
Synonyms
Therapy Description

T3011 is an oncolytic herpes simplex virus-1 (HSV-1), engineered to express the cytokine IL-12 and an antibody against PD-1, which may block the immune checkpoint, and lead to inhibition of tumor cell proliferation (NCI Drug Dictionary)

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Drug Name Trade Name Synonyms Drug Classes Drug Description
T3011 T 3011|T-3011 T3011 is an oncolytic herpes simplex virus-1 (HSV-1), engineered to express the cytokine IL-12 and an antibody against PD-1, which may block the immune checkpoint, and lead to inhibition of tumor cell proliferation (NCI Drug Dictionary)

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04370587 Phase I T3011 A Clinical Study of T3011 in Patients With Advanced Cutaneous or Subcutaneous Malignancies Recruiting USA | AUS 0
NCT04780217 Phase Ib/II T3011 Pembrolizumab + T3011 A Clinical Study of Intravenous T3011 Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors Active, not recruiting USA 0


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