Therapy Detail
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| Therapy Name | JBH492 |
| Synonyms | |
| Therapy Description |
JBH492 is an antibody-drug conjugate consisting of an antibody that targets CC chemokine receptor 7 present on tumor cells and conjugated to the maytanisoid DM4, which may lead to inhibition of tumor cell proliferation (NCI Drug Ductionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| JBH492 | JBH 492|JBH-492|Anti-CCR7 ADC JBH492 | JBH492 is an antibody-drug conjugate consisting of an antibody that targets CC chemokine receptor 7 present on tumor cells and conjugated to the maytanisoid DM4, which may lead to inhibition of tumor cell proliferation (NCI Drug Ductionary). |
Filtering
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- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04240704 | Phase I | JBH492 | Safety and Preliminary Efficacy of JBH492 Monotherapy in Patients With Chronic Lymphocytic Leukemia (CLL) and Non-Hodgkin's Lymphoma (NHL) | Terminated | ISR | FIN | ESP | DEU | 3 |
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