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Therapy Name CC-98633
Synonyms
Therapy Description

CC-98633 are T-lymphocytes engineered to express chimeric antigen receptor (CAR) that targets B-cell maturation antigen (BCMA; TNFRSF17), potentially resulting in enhanced cytokine production and antitumor activity (Blood (2022) 140 (Supplement 1): 1360-1362).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CC-98633 CC98633|CC 98633|Autologous BCMA-targeted NEX-T CAR T Cells CC-98633|BMS986354 CC-98633 are T-lymphocytes engineered to express chimeric antigen receptor (CAR) that targets B-cell maturation antigen (BCMA; TNFRSF17), potentially resulting in enhanced cytokine production and antitumor activity (Blood (2022) 140 (Supplement 1): 1360-1362).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04394650 Phase I Cyclophosphamide + Fludarabine CC-98633 A Study of CC-98633, BCMA-targeted Chimeric Antigen Receptor (CAR) T Cells, in Subjects With Relapsed and/or Refractory Multiple Myeloma Completed USA 0


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