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Therapy Name AMG 910
Synonyms
Therapy Description

AMG 910 is a bispecific T-cell engager (BiTE) that targets CLDN18.2 expressed on tumor cells, and the CD3 antigen found on cytotoxic T cell lymphocytes, potentially resulting in T cell directed lysis of tumor cells (Ann Oncol. 2020 Sep 1;31(Supple. 4):S928-S929).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
AMG 910 AMG-910|AMG910|Bispecific Antibody AMG 910 CLDN18.2 Antibody 19 AMG 910 is a bispecific T-cell engager (BiTE) that targets CLDN18.2 expressed on tumor cells, and the CD3 antigen found on cytotoxic T cell lymphocytes, potentially resulting in T cell directed lysis of tumor cells (Ann Oncol. 2020 Sep 1;31(Supple. 4):S928-S929).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04260191 Phase I AMG 910 Study of AMG 910 in Subjects With CLDN18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma Terminated USA | NLD | FRA | ESP | DEU | AUT 3


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