Therapy Detail

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Therapy Name JTX 8064 + Pimivalimab
Synonyms
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
JTX 8064 JTX-8064|JTX8064 LILRB2 Antibody 11 JTX 8064 is an antagonist monoclonal antibody targeting LILRB2, which potentially induces macrophage polarization against tumor cells (PMID: 36780212).
Pimivalimab JTX4014|JTX 4014|JTX-4014 Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 122 Pimivalimab (JTX-4014) is a monoclonal antibody that targets PD-1 (PDCD1), potentially resulting in restoration of anti-tumor immune response (NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04669899 Phase I JTX 8064 JTX 8064 + Pimivalimab JTX 8064 + Pembrolizumab Study of JTX 8064, as Monotherapy and in Combination With a PD-1 Inhibitor, in Adult Subjects With Advanced Refractory Solid Tumors Completed USA 0


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