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Therapy Name | Bevacizumab + Ixabepilone |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Bevacizumab | Avastin | VEGF Antibody 12 VEGFR Inhibitor (Pan) 36 | Avastin (bevacizumab) is a monoclonal antibody that binds VEGF and inhibits binding to VEGFR, potentially resulting in decreased tumor growth (PMID: 15136787). Avastin (bevacizumab) is FDA approved for use in colorectal cancer, non-small cell lung cancer, glioblastoma, renal cell carcinoma, cervical carcinoma, and ovarian cancer, and in combination with carboplatin and paclitaxel in epithelial ovarian, fallopian tube, or primary peritoneal cancer (FDA.gov). | |
Ixabepilone | Ixempra | Aza-epothilone B | Antimicrotubule Agent 14 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT03093155 | Phase II | Bevacizumab + Ixabepilone Ixabepilone | Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab | Completed | USA | 0 |
NCT00923130 | Phase II | Bevacizumab + Ixabepilone | Bevacizumab Plus Ixabepilone to Treat Patients With Advanced Kidney Cancer | Completed | USA | 0 |