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Therapy Name | Flutamide + Goserelin |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Flutamide | Eulexin | Flutamide USP25 | Hormone - Anti-androgens 54 | Eulexin (flutamide) is a nonsteroidal antiandrogen that competitively blocks androgen receptors. Eulexin prevents receptor activation and translocation to the nucleus, thus preventing androgen-dependent DNA and protein synthesis, which may prevent tumor cell growth (NCI Drug Dictionary). |
Goserelin | Zoladex | Goserelin acetate | Zoladex (goserelin) is a synthetic analog of lutenizing hormone-releasing hormone, which causes decreased testosterone production in males and decreased estradiol production in females, and is FDA approved for use in prostate carcinoma (FDA.gov). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04513717 | Phase III | Bicalutamide + Buserelin Buserelin + Flutamide Abiraterone + Apalutamide + Degarelix + Prednisone Abiraterone + Apalutamide + Buserelin + Prednisone Flutamide + Triptorelin Degarelix + Flutamide Abiraterone + Apalutamide + Leuprolide + Prednisone Flutamide + Leuprolide Flutamide + Goserelin Abiraterone + Apalutamide + Histrelin acetate + Prednisone Bicalutamide + Triptorelin Bicalutamide + Goserelin Flutamide + Histrelin acetate Bicalutamide + Degarelix Abiraterone + Apalutamide + Goserelin + Prednisone Abiraterone + Apalutamide + Prednisone + Triptorelin Bicalutamide + Leuprolide Bicalutamide + Histrelin acetate | Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial | Recruiting | USA | CAN | 0 |