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Therapy Name Q702
Synonyms
Therapy Description

Q702 selectively inhibits Axl, Mertk, and Csf1r, which may relieve immunosuppression in the tumor microenvironment and increase infiltration of immune cells into tumors, potentially leading to tumor regression (AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 4974)

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Q702 Q 702|Q-702 AXL Inhibitor 30 CSF1R Inhibitor 28 MERTK Inhibitor 13 Q702 selectively inhibits Axl, Mertk, and Csf1r, which may relieve immunosuppression in the tumor microenvironment and increase infiltration of immune cells into tumors, potentially leading to tumor regression (AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 4974)

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04648254 Phase I Q702 Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor in Patients With Advanced Solid Tumor Recruiting USA 0


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