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Therapy Detail
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| Therapy Name | NUV-422 |
| Synonyms | |
| Therapy Description |
NUV-422 inhibits CDK2/4/6, which may lead to cell cycle arrest and growth inhibition (NCI Thesaurus). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| NUV-422 | NUV422 | CDK2 Inhibitor 31 CDK4 Inhibitor 17 CDK6 Inhibitor 6 | NUV-422 inhibits CDK2/4/6, which may lead to cell cycle arrest and growth inhibition (NCI Thesaurus). |
Filtering
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04541225 | Phase Ib/II | NUV-422 | Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas | Terminated | USA | 0 |
| NCT05191004 | Phase Ib/II | NUV-422 Fulvestrant + NUV-422 Fulvestrant | Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC | Withdrawn | USA | 0 |
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