Therapy Detail
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| Therapy Name | GEN3014 |
| Synonyms | |
| Therapy Description |
GEN3014 (Hexabody-CD38) is a modified human monoclonal antibody against CD38 that may enhance complement dependent cytotoxicity against tumor cells (Blood (2019) 134 (Supplement_1): 3106). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| GEN3014 | Hexabody-CD38|GEN 3014|GEN 3014 | CD38 Antibody 21 | GEN3014 (Hexabody-CD38) is a modified human monoclonal antibody against CD38 that may enhance complement dependent cytotoxicity against tumor cells (Blood (2019) 134 (Supplement_1): 3106). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04824794 | Phase Ib/II | GEN3014 | GEN3014 Safety Trial in Relapsed or Refractory Hematologic Malignancies | Terminated | USA | SWE | POL | NZL | NLD | HUN | GRC | FRA | ESP | DNK | CZE | AUS | 8 |
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