Therapy Detail
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| Therapy Name | MRG004A |
| Synonyms | |
| Therapy Description |
MRG004A is an antibody-drug conjugate consisting of an anti-tissue factor (TF) monoclonal antibody conjugated to monomethyl auristatin E (MMAE), which may lead to G2/M cell cycle arrest and apoptosis of tumor cells (NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| MRG004A | MRG-004A|MRG 004A | MRG004A is an antibody-drug conjugate consisting of an anti-tissue factor (TF) monoclonal antibody conjugated to monomethyl auristatin E (MMAE), which may lead to G2/M cell cycle arrest and apoptosis of tumor cells (NCI Drug Dictionary). |
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04843709 | Phase Ib/II | MRG004A | A Study of MRG004A in Patients With Tissue Factor Positive Advanced or Metastatic Solid Tumors | Unknown status | USA | 1 |
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