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Therapy Name | AMG 404 + AMG 994 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
AMG 404 | AMG404|AMG-404|zeluvalimab | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 | AMG 404 is a monoclonal antibody that binds to and inhibits PD-1 signaling, potentially resulting in restoration of anti-tumor immune response (NCI Drug Dictionary). | |
AMG 994 | AMG994|AMG-994|Inezetamab | AMG 994 is a bispecific antibody with undisclosed targets that potentially inhibits tumor cell proliferation (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT04727554 | Phase I | AMG 404 + AMG 994 | Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumors | Completed | USA | POL | GBR | FRA | ESP | DEU | CAN | BEL | AUS | 1 |