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Therapy Name INO-5401 + Rocakinogene sifuplasmid
Synonyms
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
INO-5401 INO5401|INO 5401 INO-5401 is a DNA plasmid engineered to encode for WT1, hTERT, and PSMA, which potentially enhances antitumor immune response (J Clin Oncol 40, no. 16_suppl (June 01, 2022) 2004, Journal for ImmunoTherapy of Cancer 2020;8).
Rocakinogene sifuplasmid INO9012|INO 9012|INO-9012 Rocakinogene sifuplasmid (INO-9012) is a plasmid encoding the IL-12 protein subunits p35 and p40, which may increase antitumor immune response and decrease tumor growth (AACR; Cancer Res 2019;79(13 Suppl):Abstract nr CT114, PMID: 32208168).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04367675 Phase I INO-5401 INO-5401 + Rocakinogene sifuplasmid INO 5401 Vaccination in BRCA1/2 Mutation Carriers Recruiting USA 0


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