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Therapy Name NGM707
Synonyms
Therapy Description

NGM707 is a monoclonal antibody with dual specificity to both ILT2 and LILRB2 (ILT4), which inhibits ligand binding including both classical and non-classical MHC-I molecules, potentially resulting in the activation of an immune cell response (Cancer Res 2021;81(13_Suppl):Abstract nr LB156).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
NGM707 NGM-707|NGM 707 LILRB2 Antibody 12 NGM707 is a monoclonal antibody with dual specificity to both ILT2 and LILRB2 (ILT4), which inhibits ligand binding including both classical and non-classical MHC-I molecules, potentially resulting in the activation of an immune cell response (Cancer Res 2021;81(13_Suppl):Abstract nr LB156).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04913337 Phase Ib/II NGM707 + Pembrolizumab NGM707 Study of NGM707 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies Active, not recruiting USA 2


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