Therapy Detail
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| Therapy Name | Dupilumab + unspecified PD-L1 antibody |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Dupilumab | REGN 668|REGN-668|REGN668|SAR 231893|SAR231893|SAR-231893 | Dupilumab is a monoclonal antibody that targets IL-4Ralpha, resulting in decreased IL-4 and IL-13 signaling and potentially leading to decreased tumor cell survival (NCI Drug Dictionary). | ||
| unspecified PD-L1 antibody | Experimental PD-L1 antibody | Immune Checkpoint Inhibitor 150 PD-L1/PD-1 antibody 132 |
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05013450 | Phase Ib/II | Dupilumab + unspecified PD-L1 antibody Dupilumab + unspecified PD-1 antibody | Dupilumab_Metastatic NSCLC | Completed | USA | 0 |
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