Therapy Detail
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| Therapy Name | ASN004 |
| Synonyms | |
| Therapy Description |
ASN004 is an antibody-drug conjugate (ADC) comprising an antibody that targets 5T4 (TPBG) linked to Auristatin F hydroxypropylamide, potentially resulting in cytotoxicity of tumor cells expressing 5T4 (TPBG), inhibition of tumor growth, and tumor regression (PMID: 34045226). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ASN004 | ASN 004|ASN-004 | ASN004 is an antibody-drug conjugate (ADC) comprising an antibody that targets 5T4 (TPBG) linked to Auristatin F hydroxypropylamide, potentially resulting in cytotoxicity of tumor cells expressing 5T4 (TPBG), inhibition of tumor growth, and tumor regression (PMID: 34045226). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04410224 | Phase I | ASN004 | Study of ASN004 in Patients With Advanced Solid Tumors (ASN004) | Completed | USA | 0 |
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