Therapy Detail
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| Therapy Name | Arsenic trioxide + QTX-2101 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Arsenic trioxide | Trisenox | ATO|SDK002 | GLI1/2 inhibitor 6 | Trisenox (arsenic trioxide) has multiple mechanisms of action, including inhibition of Gli1 and Gli2 transcription factors (PMID: 26891329). Trisenox (arsenic trioxide) is FDA approved for patients with acute promyelocytic leukemia with PML-RARA translocations (FDA.gov). |
| QTX-2101 | SY 2101|SY2101|SY-2101|QTX 2101|QTX2101|ORH-2014|ORH2014|ORH 2014 | QTX-2101 is an oral formulation of arsenic trioxide, which potentially induces tumor cell apoptosis (PMID: 40020161, NCI Drug Dictionary) |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04996030 | Phase I | Arsenic trioxide + QTX-2101 QTX-2101 Arsenic trioxide | A Study for Oral SY-2101 for Participants With Acute Promyelocytic Leukemia | Suspended | USA | 0 |
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