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Therapy Name ASP0739
Synonyms
Therapy Description

ASP0739 are human artificial adjuvant vector cells loaded with the CD1d ligand alpha-galactosylceramide and modified to express the tumor associated antigen NY-ESO-1 (CTAG1B), which potentially induce activation of immune cells, and cytotoxic T-cell mediated response against tumor cells expressing NY-ESO-1 (NCI Thesaurus).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
ASP0739 aAVC ASP0739|aAVCs ASP0739|ASP 0739|ASP-0739 ASP0739 are human artificial adjuvant vector cells loaded with the CD1d ligand alpha-galactosylceramide and modified to express the tumor associated antigen NY-ESO-1 (CTAG1B), which potentially induce activation of immune cells, and cytotoxic T-cell mediated response against tumor cells expressing NY-ESO-1 (NCI Thesaurus).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04939701 Phase Ib/II ASP0739 + Pembrolizumab ASP0739 Study of ASP0739 Alone and With Pembrolizumab in Advanced Solid Tumors With NY-ESO-1 Expression Participants Terminated USA 0


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