Therapy Detail
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| Therapy Name | Montanide ISA 51 + Sargramostim + SurVaxM + Temozolomide |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Montanide ISA 51 | ||||
| Sargramostim | Leukine | GM-CSF|Prokine | ||
| SurVaxM | SVN53-67/M57-KLH | SurVaxM (SVN53-67/M57-KLH) is a peptide vaccine targeting survivin (Birc5), which may induce anti-tumor immune response (PMID: 27576783). | ||
| Temozolomide | Temodar | Methazolastone|TMZ | Chemotherapy - Alkylating 18 | Temodar (temozolomide) is a dacarbazine analog and cytotoxic alkylating agent (NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06202066 | Phase II | Montanide ISA 51 + Sargramostim + SurVaxM + Temozolomide | Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas | Not yet recruiting | USA | 0 |
| NCT05163080 | Phase II | SurVaxM + Temozolomide Montanide ISA 51 + Sargramostim + SurVaxM + Temozolomide | SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE) (SURVIVE) | Active, not recruiting | USA | 0 |
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