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Therapy Name JNJ74856665
Synonyms
Therapy Description

JNJ74856665 inhibits DHODH, which may lead to decreased proliferation and increased differentiation and apoptosis of cancer cells (Cancer Res 2021;81(13_Suppl):Abstract nr 1256).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
JNJ74856665 JNJ-74856665|JNJ 74856665 JNJ74856665 inhibits DHODH, which may lead to decreased proliferation and increased differentiation and apoptosis of cancer cells (Cancer Res 2021;81(13_Suppl):Abstract nr 1256).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04609826 Phase I JNJ74856665 Azacitidine + JNJ74856665 JNJ74856665 + Venetoclax A Study of JNJ-74856665 in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) Active, not recruiting GBR | FRA | ESP 1


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