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Therapy Name CTL-002
Synonyms
Therapy Description

CTL-002 is a neutralizing antibody that targets growth and differentiation factor 15 (GDF-15), which may lead to increased recruitment of immune cells into the tumor and tumor cell killing, and decreased tumor cell proliferation (J Clin. Oncol. 39, no. 15_suppl; NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CTL-002 CTL 002|CTL002|Visugromab CTL-002 is a neutralizing antibody that targets growth and differentiation factor 15 (GDF-15), which may lead to increased recruitment of immune cells into the tumor and tumor cell killing, and decreased tumor cell proliferation (J Clin. Oncol. 39, no. 15_suppl; NCI Drug Dictionary).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04725474 Phase I CTL-002 First-in-Human Study of the GDF-15 Neutralizing Antibody CTL-002 in Patients With Advanced Cancer (GDFATHER) (GDFATHER) Active, not recruiting ESP | DEU | CHE 0


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