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| Therapy Name | Megestrol acetate + Pterostilbene |
| Synonyms | |
| Therapy Description | |
| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Megestrol acetate | Megace | MGA|Linmegestrol|Magestin|Megestat|Megeron | Megace (megestrol acetate) is a progestin that activates progesterone receptor signaling and blocks luteinizing hormone signaling, which may lead to potential anti-estrogen and antitumor activities (PMID: 2471590). | |
| Pterostilbene | Pterostilbene is a stilbenoid that potentially functions as an antioxidant by preventing cellular damage induced by reactive oxygen species, and may have anti-inflammatory and pro-apoptotic effects (NCI Drug Dictionary). |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03671811 | Phase II | Megestrol acetate + Pterostilbene Megestrol acetate | Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy | Active, not recruiting | USA | 0 |