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Therapy Name Tigilanol tiglate
Synonyms
Therapy Description

Tigilanol tiglate is a diterpene ester that activates protein kinase C, potentially resulting in increased tumor cell death and reduced tumor growth (PMID: 25272271, PMID: 33420238).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Tigilanol tiglate EBC-46|EBC 46|EBC46|EBI 46|EBI-46|EBI46 Tigilanol tiglate is a diterpene ester that activates protein kinase C, potentially resulting in increased tumor cell death and reduced tumor growth (PMID: 25272271, PMID: 33420238).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05608876 Phase II Tigilanol tiglate A Clinical Study to Investigate the Efficacy of Tigilanol Tiglate Directly in Head and Neck Cancer Recruiting GBR | AUS 0
NCT05755113 Phase II Tigilanol tiglate A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcoma Recruiting USA 0
NCT05234437 Phase II Tigilanol tiglate A Trial of Intratumoural Tigilanol Tiglate in Adult Participants With Stage IIIB to IV M1c Melanoma Terminated AUS 0


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