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Therapy Name | Capecitabine + Enadenotucirev |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Capecitabine | Xeloda | R340 | Chemotherapy - Antimetabolite 14 | Xeloda (capecitabine) is an antimetabolite that when activated to 5-FU ultimately inhibits DNA synthesis and cell division (NCI Drug Dictionary). |
Enadenotucirev | EnAd|ColoAd1|ColoAd-1 | Enadenotucirev is a conditionally-replicating group B adenovirus that has antitumor and immunomodulating activity (PMID: 26708004, PMID: 32532291). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT03916510 | Phase I | Capecitabine + Enadenotucirev | Chemoradiation With Enadenotucirev as a Radiosensitiser in Locally Advanced Rectal Cancer (CEDAR) | Completed | GBR | 0 |