Therapy Detail
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| Therapy Name | DAN-222 |
| Synonyms | |
| Therapy Description |
DAN-222 is a polymeric nanoparticle formulation of the topoisomerase I inhibitor camptothecin, which may lead to inhibition of tumor growth (Cancer Res (2022) 82 (4_Supplement): P5-16-16). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| DAN-222 | DAN 222|DAN222 | TOPO1 inhibitor 11 | DAN-222 is a polymeric nanoparticle formulation of the topoisomerase I inhibitor camptothecin, which may lead to inhibition of tumor growth (Cancer Res (2022) 82 (4_Supplement): P5-16-16). |
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05261269 | Phase I | DAN-222 DAN-222 + Niraparib | A Dose-escalation Study of the Safety and Pharmacology of DAN-222 in Subjects With Metastatic Breast Cancer | Completed | USA | 0 |
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