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Therapy Name | BI 1831169 |
Synonyms | |
Therapy Description |
BI 1831169 is a vesicular stomatitis virus (VSV)-derived oncolytic chimeric virus containing a modified glycoprotein, which may lead to reduced neurotoxicity, increased tumor lysis, and immune cell-mediated tumor cell killing (PMID: 35699077, PMID: 24812275). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
BI 1831169 | BI1831169|BI-1831169 | BI 1831169 is a vesicular stomatitis virus (VSV)-derived oncolytic chimeric virus containing a modified glycoprotein, which may lead to reduced neurotoxicity, increased tumor lysis, and immune cell-mediated tumor cell killing (PMID: 35699077, PMID: 24812275). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT05155332 | Phase I | BI 1831169 + Ezabenlimab BI 1831169 | A Study to Test Different Doses of BI 1831169 Alone and in Combination With Ezabenlimab in People With Different Types of Advanced Cancer (Solid Tumors). | Recruiting | USA | FRA | ESP | DEU | CHE | BEL | AUT | AUS | 0 |