Therapy Detail
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| Therapy Name | INCB123667 |
| Synonyms | |
| Therapy Description |
INCB123667 selectively inhibits CDK2, potentially leading to decreased growth of CCNE-overexpressing tumors (European Journal of Cancer 174 (2022): S79). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| INCB123667 | INCB-123667|INCB 123667 | CDK2 Inhibitor 31 | INCB123667 selectively inhibits CDK2, potentially leading to decreased growth of CCNE-overexpressing tumors (European Journal of Cancer 174 (2022): S79). |
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07214779 | Phase III | Gemcitabine Topotecan INCB123667 Pegylated liposomal doxorubicin Paclitaxel | Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression (MAESTRA 2) | Recruiting | USA | POL | NLD | ITA | IRL | GBR | FRA | ESP | DEU | CHE | CAN | BEL | AUS | 1 |
| NCT07023627 | Phase II | INCB123667 | A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression | Recruiting | USA | GBR | ESP | CHE | BEL | AUS | 2 |
| NCT05238922 | Phase I | INCB123667 | Study of INCB123667 in Subjects With Advanced Solid Tumors | Recruiting | USA | NLD | ITA | GBR | FRA | CHE | 2 |
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