Therapy Detail
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| Therapy Name | XB002 |
| Synonyms | |
| Therapy Description |
XB002 is an antibody-drug conjugate (ADC) comprising a tissue factor (TF)-targeted monoclonal antibody linked to zovodotin, which potentially inhibits tumor growth (PMID: 39494690). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| XB002 | XB-002|XB 002|Samatatug zovodotin | XB002 is an antibody-drug conjugate (ADC) comprising a tissue factor (TF)-targeted monoclonal antibody linked to zovodotin, which potentially inhibits tumor growth (PMID: 39494690). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04925284 | Phase I | XB002 Nivolumab + XB002 | Study of XB002 in Subjects With Solid Tumors (JEWEL-101) | Completed | USA | NLD | ITA | GBR | FRA | ESP | BEL | AUS | 1 |
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