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| Therapy Name | AGEN1571 + Botensilimab |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| AGEN1571 | AGEN 1571|AGEN-1571 | AGEN1571 is a human monoclonal antibody that targets ILT2, potentially leading to increased pro-inflammatory cytokine secretion, immune cell activation, and enhanced antitumor immune response (Cancer Res 2022;82(12_Suppl):Abstract nr 2906). | ||
| Botensilimab | AGEN1181|AGEN 1181|AGEN-1181 | CTLA4 Antibody 33 Immune Checkpoint Inhibitor 150 | Botensilimab (AGEN1181) is an antibody that targets CTLA4, potentially resulting in increased anti-tumor immune response (Journal for ImmunoTherapy of Cancer 2021;9). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05377528 | Phase I | AGEN1571 + Balstilimab + Botensilimab AGEN1571 + Botensilimab AGEN1571 + Balstilimab AGEN1571 | Study of AGEN1571 in Participants With Advanced Solid Tumors | Completed | USA | 0 |
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